Jennifer Granick, DVM, MS, PhD, DACVIM (SAIM)

Associate Professor, Internal Medicine, Department of Veterinary Clinical Sciences
Jennifer Granick


Office Address

Lewis Small Animal Hospital
1365 Gortner Avenue
St. Paul, MN 55108
United States



PhD, University of California, Davis, 2012

DVM, University of Wisconsin, 2003

MS, University of Minnesota, 2008

BS, Northland College, 1998

Licensures and Certifications

Diplomate, American College of Veterinary Internal Medicine (Small Animal Internal Medicine), 2008


Professional Associations

  • Diplomate, American College of Veterinary Internal Medicine (Small Animal Internal Medicine), 2008
  • American Veterinary Medical Association
  • International Society of Companion Animal Infectious Disease

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Clinical interests

My clinical interests are in infectious diseases that affect cats and dogs, particularly those that also affect humans, and antimicrobial stewardship.


Research Summary/Interests

My research focuses globally on infectious disease and host immune response. I am specifically interested in the role of white blood cell precursors (hematopoietic stem and progenitor cells) outside of their bone marrow niche in response to infection. I study a model of Staphylococcus aureus skin wound infection and how these stem and progenitor cells participate in the innate immune response, specifically 1)mechanisms of differentiation to mature immune cells within the wound environment, 2)trafficking of these cells to sites of infection outside the bone marrow, and 3)how these cells influence the response of other immune cells in the wound. A technical area of expertise is multiparameter flow cytometry.

Research Funding Grants

“Endogenous Hematopoietic Stem and Progenitor Cell Function at the Site of Cutaneous Staphylococcus aureus Infection“- University of Minnesota Grant-in-Aid of Research, Artistry and Scholarship, Principal Investigator, 1/1/2014-6/30/2015


  • Carrade Holt, DD, JA Wood, JL Granick, NJ Walker, KC Clark, and DL Borjesson. (2014) Equine mesenchymal stem cells inhibit T cell proliferation through different mechanisms depending on tissue source. Stem Cells and Development. June 1;23(11):1258-65.
  • Kim, MH, F Gorouhi, S Ramirez, JL Granick, A Soulika, SI Simon, and RR Isseroff. (2014). Catecholamine stress alters neutrophil trafficking and impairs wound healing by ß2 adrenergic receptor mediated upregulation of IL-6. J. Investig. Dermatology. March; 134(3):809-17.
  • Granick JL, PC Falahee, D Dahmubed, DL Borjesson, LS Miller, SI Simon. (2013). Staphylococcus aureus signaling through TLR2 and MyD88 is required for enhanced trafficking to and myeloid differentiation in infected wounds. Blood. Sept. 5; 122(10):1170-1778.
  • CA Toupadakis, JL Granick, M Sagy, A Wong, E Ghassemi, DJ Chung, DL Borjesson2, CE Yellowley. (2013). Mobilization of endogenous stem cell populations enhances fracture healing in a murine femoral fracture model. Cytotherapy. Sept; 15(9): 1136-1147.
  • EJ Armstrong, JL Granick, SI Simon. (2013). Editorial: A missing link? Monocyte activation by uremic toxins in cardiorenal syndrome. J Leukocyte Biology. June; 93:821-23.
  • Cho JS, Guo Y, Ramos RI, Hebroni F, Plaisier SB, Xuan C, Granick JL, Matsushima H, Takashima A, Iwakura Y, Cheung AL, Cheng G, Lee DJ, Simon SI, Miller LS. (2012). Neutrophil-derived IL-1? is Sufficient for Abscess Formation in Immunity against Staphylococcus aureus in Mice. PLoS Pathogens. Nov;8(11):e1003047.
  • Granick JL, SI Simon, DL Borjesson. (2012). Hematopoietic stem and progenitor cells as effectors in innate immunity. Bone Marrow Research. 2012:165107.
  • Kim, MH*, JL Granick*, C Kwok, NJ Walker, DL Borjesson, FR Curry, L Miller, SI Simon. (2011). Neutrophil survival and c-kit+ progenitor proliferation in Staphylococcus aureus-infected skin wounds promote resolution. Blood. March; 117(12):3343-3352 *shared first authorship
  • Granick JL, PJ Armstrong, JB Bender. (2009). Anaplasma phagocytophilum infection in dogs: 34 cases (2000-2007). J Am Vet Med Assoc. Jun 15;234(12):1559-65.
  • Granick, JL, PJ Armstrong. (2009). Make your diagnosis: Diarrhea and vomiting in a Shiba Inu. Clinician’s Brief. March.
  • Granick JL, DV Reneer, JA Carylon, DL Borjesson. (2008). Anaplasma phagocytophilum infects cells of the megakaryocytic lineage through sialylated ligands but fails to alter platelet production . J Medical Microbiology. Apr;57:416-23.